Benzoic Acid → 2-Chloro-5-cyclopropylmethanesulfonyl-benzoic acid
反応式
C(O)(=O)[C:2]1[CH:7]=[CH:6][CH:5]=CC=1.[Cl:10][C:11]1[CH:19]=[CH:18][C:17]([S:20]([OH:22])=[O:21])=[CH:16][C:12]=1[C:13]([OH:15])=[O:14].BrCC1CC1.II>C1(CO)CC1>[Cl:10][C:11]1[CH:19]=[CH:18][C:17]([S:20]([CH2:5][CH:6]2[CH2:2][CH2:7]2)(=[O:22])=[O:21])=[CH:16][C:12]=1[C:13]([OH:15])=[O:14]参加物
6
実験手順
The title compound was synthesised according to the procedure described for the synthesis of 2-Chloro-5-methanesulfonyl)-benzoic acid from 2-Chloro-5-sulfino-benzoic acid and Bromomethyl-cyclopropane (+catalytic amount I2) in 20 ml cyclopropyl methanol/20 ml water and obtained in 8% yield. MS (m/e): 273.1 (MH−, 100%).
後処理
- customobtained in 8% yield
出典と根拠
- ORDレコード
- ord-6074aae533fb4a4fa4fccb4f830f50df
- 出典データセット
- uspto-grants-2008_09
- 特許番号
- US07427612B2
反応ノート
読み込み中…