1,2-Epoxybutane → 1-(p-Ethylphenoxy)-butan-2-ol

HRID 328151

反応式

HRID 328151 の反応式
[CH2:1]([C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[CH:5][CH:4]=1)[CH3:2].[CH2:10]1[O:14][CH:11]1[CH2:12][CH3:13].[OH-].[Na+]>>[CH2:1]([C:3]1[CH:8]=[CH:7][C:6]([O:9][CH2:10][CH:11]([OH:14])[CH2:12][CH3:13])=[CH:5][CH:4]=1)[CH3:2]

参加物

4

反応物 3

HCID 78341,2-EpoxybutaneHCID 14798Sodium HydroxideHCID 312424-Ethylphenol

生成物 1

HCID 214441151-(p-Ethylphenoxy)-butan-2-ol収率 76.3%

実験手順

In a closed vessel 12.2g (0.1 mol) of p-ethylphenol, 7.2 g (0.1 mol) of 1,2-butylene oxide and 0.8 ml of a 50% aqueous solution of sodium hydroxide were heated at 140° to 145° C for 4 hours in the same way as in Example 1. The reaction mixture obtained was treated in the same way as in Example 1 to afford 14.8 g of 1-(p-ethylphenoxy)-butan-2-ol (compound No. 52) in a yield of 76.3%.

後処理

  1. customThe reaction mixture obtained
  2. additionwas treated in the same way as in Example 1

出典と根拠

ORDレコード
ord-92c1464e53d14e5f99903d078d027c3e
出典データセット
uspto-grants-1977_04
特許番号
US04016186

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