Hydrogen Bromide → 1,4-Dimethyl-2-[(2-aminoethyl)thiomethyl]imidazole dihydrobromide
反応式
[CH3:1][N:2]1[CH:6]=[C:5]([CH3:7])[N:4]=[C:3]1[CH2:8]O.Cl.[NH2:11][CH2:12][CH2:13][SH:14].[BrH:15]>>[BrH:15].[BrH:15].[CH3:1][N:2]1[CH:6]=[C:5]([CH3:7])[N:4]=[C:3]1[CH2:8][S:14][CH2:13][CH2:12][NH2:11]参加物
4
実験手順
The reaction of 1,4-dimethyl-2-hydroxymethylimidazole (2.5 g.) with cysteamine hydrochloride (2.5 g.) in aqueous hydrobromic acid by the method described in Example 1 (i) (a) gave 1,4-dimethyl-2-[(2-aminoethyl)thiomethyl]imidazole dihydrobromide (6.2 g.) m.p. 161°-163° (from isopropyl alcohol-methoanol).
出典と根拠
- ORDレコード
- ord-27d6c2b808bc40f1a49850db58ead8c1
- 出典データセット
- uspto-grants-1977_04
- 特許番号
- US04018931
反応ノート
読み込み中…