Benzyl Bromide → 1-(Phenylmethyl)pyrrolidine
反応式
[NH:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:6](Br)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>CCOCC>[C:7]1([CH2:6][N:1]2[CH2:5][CH2:4][CH2:3][CH2:2]2)[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1参加物
4
実験手順
A 25.0 ml portion of pyrrolidine was reacted with 10.9 ml of benzyl bromide in ether as described in Example 3, giving 12.3 g of 1-(phenylmethyl)pyrrolidine, which was then reacted with butyl lithium and diphenylphosphine chloride as described in Example 3, giving diphenyl]2-(1-pyrrolidinylmethyl)phenyl]phosphine.
出典と根拠
- ORDレコード
- ord-9293d2e303a2441eba00c7ae2796c964
- 出典データセット
- uspto-grants-1990_01
- 特許番号
- US04892885
反応ノート
読み込み中…