N-bromobutanimide → HCID 57437663、化合物
反応式
[CH3:1][C:2]1[N:3]([C:8]2[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=2[C:10]#[N:11])[CH:4]=[C:5]([CH3:7])[N:6]=1.[Br:16]N1C(=O)CCC1=O>C(#N)C>[Br:16][C:4]1[N:3]([C:8]2[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=2[C:10]#[N:11])[C:2]([CH3:1])=[N:6][C:5]=1[CH3:7]参加物
4
実験手順
Compound 6 (5.18 grams, 26.0 mmol) was dissolved in acetonitrile (150 mL). To this was added N-bromosuccinimide (4.67 grams, 26.0 mmol). This was stirred at reflux for 1 hour before being evaporated in vacuo. The residue was dissolved in dichloromethane and washed with water. The organic layer was evaporated in vacuo to give the title compound as a yellow solid. NMR confirmed structure.
後処理
- temperatureat reflux for 1 hour
- custombefore being evaporated in vacuo
- dissolutionThe residue was dissolved in dichloromethane
- washwashed with water
- customThe organic layer was evaporated in vacuo
出典と根拠
- ORDレコード
- ord-5341eec1c5664947b43b36e2fe963c2f
- 出典データセット
- uspto-grants-2014_11
- 特許番号
- US08889864B2
反応ノート
読み込み中…