Formamide → 4-(N-formylaminomethyl)benzophenone

HRID 342791

反応式

HRID 342791 の反応式
[CH:1]([NH2:3])=[O:2].C([N-]C=O)=O.[Na+].Cl[CH2:11][C:12]1[CH:25]=[CH:24][C:15]([C:16]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[O:17])=[CH:14][CH:13]=1.C(=O)([O-])[O-].[Na+].[Na+]>C[O-].[Na+]>[CH:1]([NH:3][CH2:11][C:12]1[CH:25]=[CH:24][C:15]([C:16]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[O:17])=[CH:14][CH:13]=1)=[O:2]

参加物

6

反応物 4

HCID 713FormamideHCID 10340Sodium CarbonateHCID 30163764-(Chloromethyl)benzophenoneHCID 10877056Sodium Diformylamide

生成物 1

HCID 537210824-(N-formylaminomethyl)benzophenone

試薬・触媒・溶媒 1

HCID 10942334Sodium Methoxide溶媒

実験手順

150 g of formamide are stirred together with 90 mL of 30%ig sodium methylate solution for 8 hours under slight vacuum at 80° C. To the resulting solution of sodium diformylamide there are added 150 g of 4-chloromethylbenzophenone. After 15 hours the suspension originally present has changed to a clear solution which is added to 1l of 10%ig sodium carbonate solution. A solid material precipitates, which is filtered off in vacuo and dried.

後処理

  1. customA solid material precipitates
  2. filtrationwhich is filtered off in vacuo
  3. customdried

出典と根拠

ORDレコード
ord-f04bdcdffb864269893718aa61552b51
出典データセット
uspto-grants-1999_01
特許番号
US05859084

関連ノート

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