Hydrochloric Acid → HCID 178494817、化合物
反応式
[OH-].[Li+].[Br:3][C:4]1[NH:8][C:7]([C:9]([O:11]C)=[O:10])=[C:6](/[CH:13]=[CH:14]/[O:15][CH3:16])[N:5]=1.Cl>O.O1CCCC1>[Br:3][C:4]1[NH:8][C:7]([C:9]([OH:11])=[O:10])=[C:6](/[CH:13]=[CH:14]/[O:15][CH3:16])[N:5]=1参加物
6
実験手順
A solution of 2.20 g lithium hydroxide in 175 ml of water is added to a solution of 3.50 g methyl 2-bromo-5-(trans-2-methoxy-vinyl)-3H-imidazole-4-carboxylate in 140 ml of tetrahydrofuran. The solution is stirred for 4 h at ambient temperature. Then 92 ml aqueous 1 M hydrochloric acid are added, and the solution is cooled in the ice bath. The precipitate is separated off, washed with water and dried.
後処理
- customThe precipitate is separated off
- washwashed with water
- customdried
出典と根拠
- ORDレコード
- ord-1fa412e74e724df087c984a2acb4f5b8
- 出典データセット
- uspto-grants-2007_02
- 特許番号
- US07179809B2
反応ノート
読み込み中…