Thionyl Chloride → 5-Bromofuran-2-carbonyl chloride

HRID 34945

反応式

HRID 34945 の反応式
[Br:1][C:2]1[O:6][C:5]([C:7]([OH:9])=O)=[CH:4][CH:3]=1.S(Cl)([Cl:12])=O>C1(C)C=CC=CC=1>[Br:1][C:2]1[O:6][C:5]([C:7]([Cl:12])=[O:9])=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 685115-Bromo-2-furanecarboxylic acid

生成物 1

HCID 27570115-Bromofuran-2-carbonyl chloride

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

21.0 g of 5-bromo-2-furancarboxylic acid were suspended in 650 ml of toluene and 40 ml of thionyl chloride and the suspension was heated to reflux for 2 hours. The reaction solution was thereafter concentrated, whereby 5-bromo-2-furancarboxylic acid chloride was obtained as the residue.

後処理

  1. temperatureto reflux for 2 hours
  2. concentrationThe reaction solution was thereafter concentrated

出典と根拠

ORDレコード
ord-374bfbb4f33346df9af44276ccb38c16
出典データセット
uspto-grants-1988_08
特許番号
US04764522

関連ノート

読み込み中…