反応式
C[O:2][C:3](=[O:10])[CH2:4][NH:5][C:6]([CH3:9])([CH3:8])[CH3:7].[OH-].[Li+].Cl>O1CCOCC1.O>[C:6]([NH:5][CH2:4][C:3]([OH:10])=[O:2])([CH3:9])([CH3:8])[CH3:7]参加物
6
実験手順
To a solution of tert-Butylamino-acetic acid methyl ester (Maybridge), 122 mg (0.84 mmol) in 10 mL of dioxane was added a solution of 60 mg (2.52 mmol) of lithium hydroxide in 10 mL of water. The reaction mixture was stirred for two hours, acidified to pH=1 with 5 N HCl and concentrated to dryness to yield the crude desired product which was carried on without further purification. MS (IS) 132.1 (M+1).
後処理
- concentrationconcentrated to dryness
出典と根拠
- ORDレコード
- ord-31f8addea56842a7a11d48ec765271ec
- 出典データセット
- uspto-grants-2004_06
- 特許番号
- US06743794B2
関連ノート
読み込み中…