Anthranilic Acid → 2-Amino-4-methoxybenzoic acid

HRID 354833

反応式

HRID 354833 の反応式
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=[O:8])=[C:5]([N+:12]([O-])=O)[CH:4]=1.[NH4+].[OH-].C(O)(=O)C1C(=CC=CC=1)N>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([NH2:12])[C:6](=[CH:10][CH:11]=1)[C:7]([OH:9])=[O:8]

参加物

4

反応物 3

HCID 227Anthranilic AcidHCID 14923Ammonium HydroxideHCID 2886574-Methoxy-2-nitrobenzoic acid

生成物 1

HCID 3510102-Amino-4-methoxybenzoic acid

実験手順

A solution of 4-methoxy-2-nitrobenzoic acid (19.3 g., 97.9 mmole) of 200 ml. 1 N NH4OH was reduced overnight in presence of 5% Pd/BaCO3. The reaction mixture was filtered and acidified with acetic acid to yield 15.8 g. (96%) of the anthranilic acid, M.P. 186°-188° C.

後処理

  1. filtrationThe reaction mixture was filtered
  2. customto yield 15.8 g

出典と根拠

ORDレコード
ord-50a7b5b4e30d473090bcc1d5854a60ba
出典データセット
uspto-grants-1983_03
特許番号
US04377581

関連ノート

読み込み中…