Anthranilic Acid → 2-Amino-4-methoxybenzoic acid
反応式
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=[O:8])=[C:5]([N+:12]([O-])=O)[CH:4]=1.[NH4+].[OH-].C(O)(=O)C1C(=CC=CC=1)N>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([NH2:12])[C:6](=[CH:10][CH:11]=1)[C:7]([OH:9])=[O:8]参加物
4
実験手順
A solution of 4-methoxy-2-nitrobenzoic acid (19.3 g., 97.9 mmole) of 200 ml. 1 N NH4OH was reduced overnight in presence of 5% Pd/BaCO3. The reaction mixture was filtered and acidified with acetic acid to yield 15.8 g. (96%) of the anthranilic acid, M.P. 186°-188° C.
後処理
- filtrationThe reaction mixture was filtered
- customto yield 15.8 g
出典と根拠
- ORDレコード
- ord-50a7b5b4e30d473090bcc1d5854a60ba
- 出典データセット
- uspto-grants-1983_03
- 特許番号
- US04377581
反応ノート
読み込み中…