Hydrogen Peroxide → 2-Propylpyridine 1-oxide
反応式
[CH2:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][N:5]=1)[CH2:2][CH3:3].[OH:10]O.[OH-].[Na+]>C(O)(=O)C>[CH2:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][N+:5]=1[O-:10])[CH2:2][CH3:3]参加物
5
反応条件
- 温度
- 65 °C
実験手順
20 ml of 2-n-propylpyridine were dissolved in 60 ml of glacial acetic acid, mixed with 40 ml of H2O2 (30%) and stirred for 16 hours at room temperature and 3 hours at 65° C. The acetic acid was then partly rotated out, the residue was adjusted to pH 8 with NaOH (20%), extracted with dichloromethane and the organic phase rotated in to dryness. 20 g of crude 2-propylpyridine-N-oxide were obtained.
後処理
- extractionextracted with dichloromethane
出典と根拠
- ORDレコード
- ord-714f282edb704764ad9a8be82d432e6d
- 出典データセット
- uspto-grants-1991_03
- 特許番号
- US04997835
反応ノート
読み込み中…