2,6-Dichloropyridine → 2-Chloro-6-hydrazinopyridine

HRID 358582

反応式

HRID 358582 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4](Cl)[N:3]=1.O.[NH2:10][NH2:11]>CO>[NH:10]([C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[N:3]=1)[NH2:11]

参加物

4

反応物 2

HCID 169892,6-DichloropyridineHCID 24654Hydrazine hydrate (1:1)

生成物 1

HCID 3200042-Chloro-6-hydrazinopyridine

試薬・触媒・溶媒 1

HCID 887Methanol溶媒2 回

実験手順

2 g of 2,6-dichloropyridine were dissolved in 60 ml of methanol and mixed with 10 ml of 80% hydrazine hydrate. The solution was firstly stirred for 3 days at room temperature and then refluxed for 10 days. Rotation in took place, the residue was taken up with methanol, followed by rotation in again and finally recrystallization from methanol/water. 0.25 g of 2-hydrazino-6-chloropyridine was obtained.

後処理

  1. temperaturerefluxed for 10 days
  2. customfinally recrystallization from methanol/water

出典と根拠

ORDレコード
ord-c51d8063c54a4e6b814342ca1f318ddc
出典データセット
uspto-grants-1991_03
特許番号
US04997835

関連ノート

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