Acetone Cyanohydrin → 2-((4-Hydroxybutyl)amino)-2-methylpropanenitrile

HRID 35945

反応式

HRID 35945 の反応式
[CH3:1][C:2]([CH3:6])(O)[C:3]#[N:4].[NH2:7][CH2:8][CH2:9][CH2:10][CH2:11][OH:12]>C(Cl)Cl>[OH:12][CH2:11][CH2:10][CH2:9][CH2:8][NH:7][C:2]([CH3:6])([CH3:1])[C:3]#[N:4]

参加物

4

反応物 2

HCID 6406Acetone CyanohydrinHCID 258684-Amino-1-butanol

生成物 1

HCID 155119612-((4-Hydroxybutyl)amino)-2-methylpropanenitrile

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

反応条件

温度
20 °C

実験手順

220 μl of acetone cyanohydrin and 200 μl of 4-amino 1-butanol were mixed together with stirring for 16 hours at 20° C. and then was diluted with 2 ml of methylene chloride, dried, filtered and the filtrate was concentrated under reduced pressure to obtain the propanonitrile which was used as is for the following stage.

後処理

  1. customdried
  2. filtrationfiltered
  3. concentrationthe filtrate was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-af507ea0ea16417b8b65e6f6abd9ae52
出典データセット
uspto-grants-1995_05
特許番号
US05411981

関連ノート

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