Phenol → HCID 57173787、化合物

HRID 359612

反応式

HRID 359612 の反応式
[CH:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[OH:10])=[CH:2][CH3:3].[C:11]1([OH:17])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.[CH2:18](Br)[CH:19]=[CH2:20].Br[CH2:23]Br>>[CH:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[O:10][CH2:23][O:17][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[CH:20]=[CH:19][CH3:18])=[CH:2][CH3:3]

参加物

5

反応物 4

HCID 996PhenolHCID 3024DibromomethaneHCID 7841Allyl bromideHCID 930292-Propenylphenol

生成物 1

HCID 57173787HCID 57173787、化合物

実験手順

The preparation of 2-propenylphenol from phenol and allyl bromide is similar to that outlined1. The reaction of this compound with dibromomethane is similar to that described above for di (N-phenylcarboxaldimine-4-phenoxy)methane. The title compound was extracted with ether 3×100 ml portions from the aqueous dimethylformamide solution, washed with aqueous potassium hydroxide (10%) and then water. The ether phase was dried over sodium sulphate and the solvent was stripped off under reduced pressure. The oil which contained some (~5%) of a less polar component and at least two isomeric forms of the title compound, as indicated from high pressure liquid chromatography, was used without further purification in the reaction below.

後処理

  1. extractionThe title compound was extracted with ether 3×100 ml portions from the aqueous dimethylformamide solution
  2. washwashed with aqueous potassium hydroxide (10%)
  3. dry with materialThe ether phase was dried over sodium sulphate
  4. customwas used without further purification in the reaction below

出典と根拠

ORDレコード
ord-35b23179de3e4e17a12734ba84fc7665
出典データセット
uspto-grants-1991_03
特許番号
US05001294

関連ノート

読み込み中…