Phenol → Di-(2-propenylphenoxy) methane

反応式

[CH:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[OH:10])=[CH:2][CH3:3].[C:11]1([OH:17])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.[CH2:18](Br)[CH:19]=[CH2:20].Br[CH2:23]Br>>[CH:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[O:10][CH2:23][O:17][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[CH:20]=[CH:19][CH3:18])=[CH:2][CH3:3]

参加物

反応物 4

HCID 996Phenol

HCID 3024Dibromomethane

HCID 7841Allyl bromide

HCID 930292-Propenylphenol

生成物 1

HCID 57173787Di-(2-propenylphenoxy) methane

実験手順

The preparation of 2-propenylphenol from phenol and allyl bromide is similar to that outlined1. The reaction of this compound with dibromomethane is similar to that described above for di (N-phenylcarboxaldimine-4-phenoxy)methane. The title compound was extracted with ether 3×100 ml portions from the aqueous dimethylformamide solution, washed with aqueous potassium hydroxide (10%) and then water. The ether phase was dried over sodium sulphate and the solvent was stripped off under reduced pressure. The oil which contained some (~5%) of a less polar component and at least two isomeric forms of the title compound, as indicated from high pressure liquid chromatography, was used without further purification in the reaction below.