Water → Propionitrile, 3-(p-chlorophenoxy)-

HRID 361716

反応式

HRID 361716 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.[C:9](#[N:12])[CH:10]=[CH2:11].[OH-].C([N+](C)(C)C)C1C=CC=CC=1.O>CO>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:11][CH2:10][C:9]#[N:12])=[CH:4][CH:3]=1

参加物

6

反応物 4

HCID 962WaterHCID 46844-ChlorophenolHCID 7855AcrylonitrileHCID 66854Benzyltrimethylammonium hydroxide

生成物 1

HCID 96550Propionitrile, 3-(p-chlorophenoxy)-

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

A mixture of p-chlorophenol (25 g), acrylonitrile (30 ml) and a solution of benzyltrimethylammonium hydroxide (8 ml of a 40 wt % solution in methanol) were heated at reflux over the weekend. The reaction mixture was poured into water and extracted with ethyl acetate. The ethyl acetate extract was dried and evaporated to give 3-(4-chlorophenoxy)propionitrile.

後処理

  1. temperatureat reflux over the weekend
  2. extractionextracted with ethyl acetate
  3. extractionThe ethyl acetate extract
  4. customwas dried
  5. customevaporated

出典と根拠

ORDレコード
ord-525446a4cf4c4e54862c339880ef50f7
出典データセット
uspto-grants-1999_02
特許番号
US05866611

関連ノート

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