Methyl 3-allyl-4-hydroxybenzoate → Methyl 4-hydroxy-3-propylbenzoate

HRID 363038

反応式

HRID 363038 の反応式
[OH:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:4][C:3]=1[CH2:12][CH:13]=[CH2:14]>CCOC(C)=O.[Pd]>[OH:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:4][C:3]=1[CH2:12][CH2:13][CH3:14]

参加物

4

反応物 1

HCID 939882Methyl 3-allyl-4-hydroxybenzoate

生成物 1

HCID 11805593Methyl 4-hydroxy-3-propylbenzoate

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 8857Ethyl Acetate溶媒

実験手順

To 22-3 (6.0 g, 33.2 mmol) in 50 mL of EtOAc was added 60 mg of 5% Pd on carbon and the whole was hydrogenated at atmospheric pressure for 24 h. Hydrogen was removed from the reaction mixture and the solution was filtered through Celite. Evaporation of the solvent afforded product 22-4 as a white solid.

後処理

  1. customHydrogen was removed from the reaction mixture
  2. filtrationthe solution was filtered through Celite
  3. customEvaporation of the solvent

出典と根拠

ORDレコード
ord-f01451e0f3f640d8932c8f76d798ecf0
出典データセット
uspto-grants-1999_02
特許番号
US05872138

関連ノート

読み込み中…