Sulfuric Acid → Azelaic Acid
反応式
[C:1]([CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]([OH:12])=[O:11])#N.[OH-:13].[Na+].S(=O)(=O)(O)[OH:16]>C(O)CO.COC.O>[C:10]([OH:12])(=[O:11])[CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][C:1]([OH:16])=[O:13]参加物
6
実験手順
83.5 g of 8-cyanooctanoic acid dissolved in 300 ml of dimethyl ether ethylene glycol are heated to 130° C. for 4 hours in the presence of 50g of 40% caustic soda. After cooling, the reaction mixture is diluted with water, then acidified to pH 5 with diluted sulfuric acid, and then the precipitated solid is filtered. After drying, 92 g of azelaic acid with a m.p. of 107° C. are obtained.
後処理
- temperatureAfter cooling
- filtrationthe precipitated solid is filtered
- customAfter drying
出典と根拠
- ORDレコード
- ord-106c0db6ab624e2f871a05c8c526b87c
- 出典データセット
- uspto-grants-1999_02
- 特許番号
- US05872267
反応ノート
読み込み中…