(Aminomethyl)phosphonic acid → Glyphosate
反応式
[NH2:1][CH2:2][P:3](=[O:6])([OH:5])[OH:4].O.[C:8]([OH:12])(=[O:11])[CH:9]=O>[Pd]>[NH2:1][CH2:2][P:3](=[O:4])([OH:6])[OH:5].[CH2:9]([NH:1][CH2:2][P:3]([OH:5])([OH:4])=[O:6])[C:8]([OH:12])=[O:11]参加物
5
実験手順
Aminomethylphosphonic acid was reductively alkylated with glyoxylic acid hydrate under catalytic hydrogenation conditions in the manner described in Example 2, except that the catalyst used was palladium metal (0.05 g), and the pH of the initial reaction mixture was 4.5. A 27% conversion of aminomethylphosphonic acid was obtained with a 93.7% selectivity to glyphosate.
後処理
- customthe pH of the initial reaction mixture
出典と根拠
- ORDレコード
- ord-6b0ffd800a764d7a9a88d4527dff1c5a
- 出典データセット
- uspto-grants-1999_02
- 特許番号
- US05874612
反応ノート
読み込み中…