(Aminomethyl)phosphonic acid → Glyphosate

HRID 363808

反応式

HRID 363808 の反応式
[NH2:1][CH2:2][P:3](=[O:6])([OH:5])[OH:4].O.[C:8]([OH:12])(=[O:11])[CH:9]=O>[Pd]>[NH2:1][CH2:2][P:3](=[O:4])([OH:6])[OH:5].[CH2:9]([NH:1][CH2:2][P:3]([OH:5])([OH:4])=[O:6])[C:8]([OH:12])=[O:11]

参加物

5

反応物 2

HCID 14017(Aminomethyl)phosphonic acidHCID 15620607Glyoxylic acid, monohydrate

生成物 2

HCID 3496GlyphosateHCID 14017(Aminomethyl)phosphonic acid

試薬・触媒・溶媒 1

HCID 23938Palladium触媒

実験手順

Aminomethylphosphonic acid was reductively alkylated with glyoxylic acid hydrate under catalytic hydrogenation conditions in the manner described in Example 2, except that the catalyst used was palladium metal (0.05 g), and the pH of the initial reaction mixture was 4.5. A 27% conversion of aminomethylphosphonic acid was obtained with a 93.7% selectivity to glyphosate.

後処理

  1. customthe pH of the initial reaction mixture

出典と根拠

ORDレコード
ord-6b0ffd800a764d7a9a88d4527dff1c5a
出典データセット
uspto-grants-1999_02
特許番号
US05874612

関連ノート

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