Pyridine → Glycidyl benzoate

HRID 364254

反応式

HRID 364254 の反応式
[CH2:1]1[O:3][CH:2]1[CH2:4][OH:5].N1C=CC=CC=1.[C:12](Cl)(=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>CCOCC>[C:12]([O:5][CH2:4][CH:2]1[O:3][CH2:1]1)(=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

参加物

5

反応物 3

HCID 1049PyridineHCID 7412Benzoyl chlorideHCID 11164Glycidol

生成物 1

HCID 25998Glycidyl benzoate収率 60%

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

A mixture containing 14.8 g (0.2 mole) of glycidol, 150 ml of anhydrous ether, 16 g (0.4 mole) of pyridine and 28 g (0.2 mole) of benzoyl chloride was stirred at room temperature for 2 hours. The mixture was filtered and the ether was evaporated to leave an oil. This oil was distilled to give 21 g (60%) of colorless oil: b.p. 92° C./0.5 mm Hg. The NMR and IR spectra were consistent with the assigned structure.

後処理

  1. filtrationThe mixture was filtered
  2. customthe ether was evaporated
  3. customto leave an oil
  4. distillationThis oil was distilled

出典と根拠

ORDレコード
ord-c63f62e849684cd993425acaf0a156f2
出典データセット
uspto-grants-1986_08
特許番号
US04604481

関連ノート

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