Barium → 4-(1H-Imidazol-2-yl)-pyridine
反応式
[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[NH:8][CH2:9][CH2:10][N:11]=2)=[CH:3][CH:2]=1.[Ba]>C(Cl)Cl>[NH:8]1[CH:9]=[CH:10][N:11]=[C:7]1[C:4]1[CH:5]=[CH:6][N:1]=[CH:2][CH:3]=1参加物
4
実験手順
2-(4-pyridyl)-imidazoline (7.0 g, 0.047M) and barium mangnate (52.5 g) in CH2Cl2 (500 ml) were refluxed with stirring for 24 hrs. The reaction mixture was then filtered through diatomaceous earth, washed with methylene chloride and then ethylacetate. The combined filtrates were concentrated and crystallized from ethylacetate-petroleum ether to give 4-(1H-imidazol-2-yl)pyridine (4.7 g, 67% yield).
後処理
- filtrationThe reaction mixture was then filtered through diatomaceous earth
- washwashed with methylene chloride
- concentrationThe combined filtrates were concentrated
- customcrystallized from ethylacetate-petroleum ether
出典と根拠
- ORDレコード
- ord-8d2006b4e8cb47d7b5b819625280b916
- 出典データセット
- uspto-grants-1986_08
- 特許番号
- US04605744
反応ノート
読み込み中…