1,2-Dimethylhydrazine → 3-Hydroxy-1,2,4-trimethyl-5-pyrazolone
反応式
[CH3:1][CH:2]([C:8]([O:10]CC)=O)[C:3](OCC)=[O:4].[CH3:13][NH:14][NH:15][CH3:16].C[O-].[Na+]>CO>[OH:10][C:8]1[N:14]([CH3:13])[N:15]([CH3:16])[C:3](=[O:4])[C:2]=1[CH3:1]参加物
5
実験手順
Diethyl methylmalonate and N,N'-dimethylhydrazine are heated under reflux for 170 hours in methanol in the presence of sodium methylate under an atmosphere of nitrogen. 3-Hydroxy-1,2,4-trimethyl-5-pyrazolone is obtained in the form of colorless crystals which, after recrystallization from ethyl acetate, melt at 87°-89° C.
出典と根拠
- ORDレコード
- ord-da58efdd8cfd44639ad1ce4e0173a134
- 出典データセット
- uspto-grants-1986_08
- 特許番号
- US04608383
反応ノート
読み込み中…