Thionyl Chloride → 3-(3-Pyridyl)acryloyl chloride hydrochloride

HRID 36548

反応式

HRID 36548 の反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=[CH:8][C:9]([OH:11])=O)[CH:2]=1.S(Cl)([Cl:14])=O>C1C=CC=CC=1>[ClH:14].[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=[CH:8][C:9]([Cl:14])=[O:11])[CH:2]=1

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 1019843-(3-Pyridinyl)-2-propenoic acid

生成物 1

HCID 713600273-(3-Pyridyl)acryloyl chloride hydrochloride

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

67 ml of benzene was added to 10 grams of 3-(3-pyridyl)-acrylic acid. 8.1 ml of thionyl chloride was added dropwise slowly thereto at ambient temperature. The temperature was elevated to 70° C. and the heating was continued until foaming ceased. Benzene and thionyl chloride were distilled off and the residue was dried thoroughly under reduced pressure.

後処理

  1. customat ambient temperature
  2. customwas elevated to 70° C.
  3. distillationBenzene and thionyl chloride were distilled off
  4. customthe residue was dried thoroughly under reduced pressure

出典と根拠

ORDレコード
ord-c47a2810ac0e4dcd8f71084b2669a25f
出典データセット
uspto-grants-1995_05
特許番号
US05415780

関連ノート

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