Hydrogen Bromide → HCID 14938892、化合物

HRID 3688ノート

反応式

HRID 3688 の反応式
[CH3:1][C:2]1[S:3][C:4]([Si](C)(C)C)=[CH:5][C:6]=1[C:7]1[C:11]([F:13])([F:12])[C:10]([F:15])([F:14])[C:9]([F:17])([F:16])[C:8]=1[C:18]1[CH:22]=[C:21]([Si](C)(C)C)[S:20][C:19]=1[CH3:27].Br>C(Cl)(Cl)Cl>[CH3:27][C:19]1[S:20][CH:21]=[CH:22][C:18]=1[C:8]1[C:9]([F:16])([F:17])[C:10]([F:14])([F:15])[C:11]([F:13])([F:12])[C:7]=1[C:6]1[CH:5]=[CH:4][S:3][C:2]=1[CH3:1]

参加物

4

反応物 2

HCID 260Hydrogen BromideHCID 149388931,2-Bis(2-methyl-5-trimethylsilyl-3-thienyl)hexafluorocyclopentene

生成物 1

HCID 14938892HCID 14938892、化合物収率 98%

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒

実験手順

1,2-bis(2-methyl-5-trimethylsilyl-3-thienyl)hexafluorocyclopentene (2.16 g, 0.005 mol) was dissolved in chloroform (200 ml) and was allowed to react for 6 hours under refluxing conditions by adding concentrated hydrobromic acid (10 ml) to the solution. After the completion of the reaction, the chloroform layer was washed with an aqueous solution of sodium bicarbonate and the chloroform was removed under reduced pressures. The reaction product was purified by silicagel column chromatogram to give 1,2-bis(2-methyl-3-thienyl)hexafluorocyclopentene (1.8 g, 0.0049 mol).

後処理

  1. customto react for 6 hours under refluxing conditions
  2. customAfter the completion of the reaction
  3. washthe chloroform layer was washed with an aqueous solution of sodium bicarbonate
  4. customthe chloroform was removed under reduced pressures
  5. customThe reaction product was purified by silicagel column chromatogram

出典と根拠

ORDレコード
ord-24790d511c784f0cb5c8390c2b1741e2
出典データセット
uspto-grants-1998_03
特許番号
US05734065

反応ノート

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