Diethylcarbamoyl chloride → HCID 20354992、化合物
反応式
[CH2:1]([S:3][C:4]1[N:8]=[CH:7][NH:6][N:5]=1)[CH3:2].[CH2:9]([N:11]([CH2:15][CH3:16])[C:12](Cl)=[O:13])[CH3:10].O1CCCC1.C(N(CC)CC)C>CCOCC>[CH2:9]([N:11]([CH2:15][CH3:16])[C:12]([N:6]1[CH:7]=[N:8][C:4]([S:3][CH2:1][CH3:2])=[N:5]1)=[O:13])[CH3:10]参加物
6
実験手順
A mixture of 6.45 g. 3-ethylthio-1,2,4-triazole, 7.5 g. diethylcarbamoyl chloride, 40 ml. dry tetrahydrofuran and 7.75 ml. dry triethylamine was refluxed under anhydrous conditions for 22 hours. The reaction mixture was worked up as described in Example 1, using ether in place of methylene dichloride, to give a residual oil. This oil was distilled under reduced pressure to give 1-diethylcarbamoyl-3-ethylthio-1,2,4-triazole, b.p. 110° - 111° C./0.2 mm. (93.6% 1-isomer by GLC assay). Elemental analysis satisfactory.
後処理
- additionA mixture of 6.45 g
- customto give a residual oil
- distillationThis oil was distilled under reduced pressure
出典と根拠
- ORDレコード
- ord-769b4531b7d6442eb8515ccf638d2f61
- 出典データセット
- uspto-grants-1978_05
- 特許番号
- US04087269
反応ノート
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