Thionyl Chloride → HCID 13597868、化合物

HRID 374422

反応式

HRID 374422 の反応式
[Br:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[C:8]([OH:10])=O.S(Cl)([Cl:13])=O>>[Br:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[C:8]([Cl:13])=[O:10]

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 8179723-Bromoisonicotinic acid

生成物 1

HCID 13597868HCID 13597868、化合物

実験手順

3-Bromopyridine-4-carboxylic acid (5.0 g) was dissolved in thionyl chloride (50 ml) and the solution heated under reflux for 4 hours, cooled and evaporated in vacuo. Re-evaporation of added toluene gave 3-bromopyridine4-carbonyl chloride, m.p.151°-154° C. (dec.) (5.45 g) as a green solid.

後処理

  1. temperaturethe solution heated
  2. temperatureunder reflux for 4 hours
  3. temperaturecooled
  4. customevaporated in vacuo

出典と根拠

ORDレコード
ord-f8192f4fac954ba7bd348f63b541c8bf
出典データセット
uspto-grants-1996_01
特許番号
US05480857

関連ノート

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