Trifluoroacetic acid → Caprine
反応式
C([O:5][C:6](=[O:13])[C@H:7]([CH2:9][CH2:10][CH2:11][CH3:12])[NH2:8])(C)(C)C.FC(F)(F)C(O)=O>ClCCl>[NH2:8][C@H:7]([C:6]([OH:13])=[O:5])[CH2:9][CH2:10][CH2:11][CH3:12]参加物
4
実験手順
23.5 mg of L-N-[(2R or S)-5-ethylthio-2-(1-naphthylmethyl)pentanoyl]norleucine tert-butyl ester was dissolved in 0.2 ml of dichloromethane, and 0.1 ml of trifluoro acetic acid was added thereto. The mixture was stirred at room temperature for four hours. Then, the reaction solution was concentrated under reduced pressure to obtain 20.7 mg of L-N-[(2R or S)-5-ethylthio-2-(1-naphthylmethyl)pentanoyl]norleucine as colorless solid.
後処理
- concentrationThen, the reaction solution was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-aa312e5f1bd544c6952f2a6f19a3f20f
- 出典データセット
- uspto-grants-1996_01
- 特許番号
- US05481036
反応ノート
読み込み中…