Trifluoroacetic acid → Caprine

HRID 374684

反応式

HRID 374684 の反応式
C([O:5][C:6](=[O:13])[C@H:7]([CH2:9][CH2:10][CH2:11][CH3:12])[NH2:8])(C)(C)C.FC(F)(F)C(O)=O>ClCCl>[NH2:8][C@H:7]([C:6]([OH:13])=[O:5])[CH2:9][CH2:10][CH2:11][CH3:12]

参加物

4

反応物 2

HCID 6422Trifluoroacetic acidHCID 12451446tert-butyl (2S)-2-aminohexanoate

生成物 1

HCID 21236Caprine

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

23.5 mg of L-N-[(2R or S)-5-ethylthio-2-(1-naphthylmethyl)pentanoyl]norleucine tert-butyl ester was dissolved in 0.2 ml of dichloromethane, and 0.1 ml of trifluoro acetic acid was added thereto. The mixture was stirred at room temperature for four hours. Then, the reaction solution was concentrated under reduced pressure to obtain 20.7 mg of L-N-[(2R or S)-5-ethylthio-2-(1-naphthylmethyl)pentanoyl]norleucine as colorless solid.

後処理

  1. concentrationThen, the reaction solution was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-aa312e5f1bd544c6952f2a6f19a3f20f
出典データセット
uspto-grants-1996_01
特許番号
US05481036

関連ノート

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