1,2-Dibromoethene → HCID 178429024、化合物

HRID 382847ノート

反応式

HRID 382847 の反応式
[Br:1]C=CBr.[Mg:5].[CH3:6][C:7]1([CH2:15][CH2:16]Br)[O:12][CH2:11][C:10]([CH3:14])([CH3:13])[CH2:9][O:8]1>O1CCCC1>[Br:1][Mg:5][CH2:16][CH2:15][C:7]1([CH3:6])[O:8][CH2:9][C:10]([CH3:14])([CH3:13])[CH2:11][O:12]1

参加物

5

反応物 3

HCID 108971,2-DibromoetheneHCID 27779132-(2-Bromoethyl)-2,5,5-trimethyl-1,3-dioxaneHCID 5462224Magnesium

生成物 1

HCID 178429024HCID 178429024、化合物

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒2 回

実験手順

In a nitrogen atmosphere, 5 ml of tetrahydrofuran and 0.1 ml of dibromoethylene were added to 3.4 g of metallic magnesium, the mixture was ice-cooled, and 30.0 g of 2,5,5-trimethyl-2-(2-bromoethyl)-1,3-dioxane and 75 ml of tetrahydrofuran were added dropwise to that mixture simultaneously over 1.5 hours. After completion of the dropping, the mixture was stirred for 1 hour with ice cooling and further at room temperature for 30 minutes to give bromo[2-(2,5,5-trimethyl-1,3-dioxan-2-yl)ethyl]magnesium (1.16 mol/l, tetrahydrofuran solution).

後処理

  1. temperaturecooled

出典と根拠

ORDレコード
ord-139d83934bc14e81a5ff610a6b8ab1b4
出典データセット
uspto-grants-2001_10
特許番号
US06310225B1

反応ノート

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