Iodine → Muconic Acid

HRID 385208

反応式

HRID 385208 の反応式
[C:1]([OH:10])(=[O:9])/[CH:2]=[CH:3]\[CH:4]=[CH:5]\[C:6]([OH:8])=[O:7].II>C(O)CC>[C:1]([OH:10])(=[O:9])/[CH:2]=[CH:3]/[CH:4]=[CH:5]/[C:6]([OH:8])=[O:7]

参加物

4

反応物 2

HCID 807IodineHCID 5280614(2E,4Z)-2,4-Hexadienedioic acid

生成物 1

HCID 5356793Muconic Acid収率 73%

試薬・触媒・溶媒 1

HCID 10311-Propanol溶媒

実験手順

cis,trans-Muconic acid (103 mg, 0.725 mmol) is dissolved in n-propanol (10 mL) at room temperature and a crystal of iodine (10 mg, 0.04 mmol) is added. The reaction mixture is allowed to stir at room temperature for 24 hours. The precipitate is filtered, washed with acetonitrile and dried under reduced pressure to yield 75 mg of trans,trans-muconic acid, a 73 percent yield.

後処理

  1. filtrationThe precipitate is filtered
  2. washwashed with acetonitrile
  3. customdried under reduced pressure

出典と根拠

ORDレコード
ord-43b6087262e946d986e929fdc93548e2
出典データセット
uspto-grants-2013_02
特許番号
US08367858B2

関連ノート

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