Water → 2-Hydroxy-1-(3-methylphenyl)ethan-1-one

HRID 389896

反応式

HRID 389896 の反応式
Br[CH2:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([CH3:11])[CH:6]=1)=[O:4].[OH2:12]>C(#N)C>[OH:12][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([CH3:11])[CH:6]=1)=[O:4]

参加物

4

反応物 2

HCID 962WaterHCID 100361292-Bromo-1-(3-methylphenyl)ethan-1-one

生成物 1

HCID 183729052-Hydroxy-1-(3-methylphenyl)ethan-1-one

試薬・触媒・溶媒 1

HCID 6342Acetonitrile溶媒

実験手順

A solution of 2-bromo-1-(3-methylphenyl)ethanone (1 g) in acetonitrile (2.5 mL) and water (13 mL) is treated under microwave irradiation (125° C., 50 min). The same experiment is repeated three times. All the vials are collected, extracted with DCM, dried over magnesium sulfate and concentrated under vacuum to give the desired compound.

後処理

  1. customAll the vials are collected
  2. extractionextracted with DCM
  3. dry with materialdried over magnesium sulfate
  4. concentrationconcentrated under vacuum

出典と根拠

ORDレコード
ord-53b1fb3a11334045a8e1fdc82626b016
出典データセット
uspto-grants-2013_02
特許番号
US08383608B2

関連ノート

読み込み中…