Dichloromethane → (3-Chloropropoxy)trimethylsilane
反応式
Cl[Si:2]([CH3:5])([CH3:4])[CH3:3].[CH:6]([O:9]C(C)C)(C)[CH3:7].Cl[CH2:14][Cl:15]>>[Cl:15][CH2:14][CH2:7][CH2:6][O:9][Si:2]([CH3:5])([CH3:4])[CH3:3]参加物
4
実験手順
A solution of chlorotrimethylsilane (126.40 g, 1.164 mol) in dichloromethane (300 L) is then added dropwise maintaining the temperature between 0° C. and 5° C. When the conversion is complete, diisopropyl ether (600 mL) is added and triethylamine hydrochloride is filtered washing the pad with diisopropyl ether. The filtrate is concentrated at 38° C. under reduced pressure and the product is purified by distillation (0-5 mmHg, 70° C.). (3-Chloropropoxy)trimethylsilane is obtained as a colourless liquid (144.57 g, 0.867 mol, 82%).
後処理
- temperaturemaintaining the temperature between 0° C. and 5° C
- filtrationtriethylamine hydrochloride is filtered
- washwashing the pad with diisopropyl ether
- concentrationThe filtrate is concentrated at 38° C. under reduced pressure
- distillationthe product is purified by distillation (0-5 mmHg, 70° C.)
出典と根拠
- ORDレコード
- ord-cf8539c716264827b4820d69894eeb95
- 出典データセット
- uspto-grants-2013_02
- 特許番号
- US08383809B2
反応ノート
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