Thionyl Chloride → 2-Chlorotrityl chloride

反応式

[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)O.S(Cl)([Cl:24])=O>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[Cl:24]

参加物

反応物 2

HCID 24386Thionyl Chloride

HCID 298659(2-Chlorophenyl)diphenylmethanol

生成物 1

HCID 945242-Chlorotrityl chloride収率 82%

実験手順

Following the procedure outlined in Example 4, 5.00 g (17.1 mmol) of (2-chlorophenyl) diphenyl methanol, designated as T-3 on Appendix A, was treated with 2.5 ml thionyl chloride (34 mmol) according to general method B to give 4.39 g (82%) of (2-Chlorophenyl) diphenyl chloromethane, mp: 131° C.

出典と根拠

ORDレコード: ord-4d903e8bd7e34041a3d7ddc86464de98
出典データセット: uspto-grants-2004_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06803375B1

反応ノート

読み込み中…