1-Hexanol → N1-(1-Methylethyl)-1,4-benzenediamine

反応式

[CH:1]([NH:4][C:5]1[CH:10]=[CH:9][C:8]([N:11]=O)=[CH:7][CH:6]=1)([CH3:3])[CH3:2].[OH-].[Na+].C(O)CCCCC>>[CH:1]([NH:4][C:5]1[CH:10]=[CH:9][C:8]([NH2:11])=[CH:7][CH:6]=1)([CH3:3])[CH3:2]

参加物

反応物 3

HCID 81031-Hexanol

HCID 14798Sodium Hydroxide

HCID 21909787N-isopropyl-4-nitrosoaniline

生成物 1

HCID 85306N1-(1-Methylethyl)-1,4-benzenediamine

実験手順

Following essentially the procedure of Example 1, 66.0 g (0.25 mole) N-isopropyl-4-nitrosoaniline, 20 g (50%) sodium hydroxide and 264 g n-hexanol were kept at 100° C. for 1.5 hours. HPLC analysis of the reaction mixture indicated absence of the nitroso starting compound. By vacuum distillation (95°-101° C. at 13.3-26.6 Pa), 31.3 g of product were recovered (48.6 wt. % yield).