反応式
[CH:1]([C:4]1[NH:5][C:6]2[C:11]([C:12]=1[CH:13]=[O:14])=[CH:10][CH:9]=[C:8]([O:15][CH3:16])[CH:7]=2)([CH3:3])[CH3:2].Br[CH2:18][C:19]1[CH:20]=[N:21][CH:22]=[CH:23][CH:24]=1.Br.[F:26][C:27]1[CH:28]=[C:29]([CH:32]=[CH:33][C:34]=1[F:35])[CH2:30][NH2:31].[CH:36]1(Br)[CH2:39]C[CH2:37]1>>[CH:16]1([O:15][C:8]2[CH:7]=[C:6]3[C:11]([C:12]([C:13]([NH:31][CH2:30][C:29]4[CH:32]=[CH:33][C:34]([F:35])=[C:27]([F:26])[CH:28]=4)=[O:14])=[C:4]([CH:1]([CH3:3])[CH3:2])[N:5]3[CH2:18][C:19]3[CH:20]=[N:21][CH:22]=[CH:23][CH:24]=3)=[CH:10][CH:9]=2)[CH2:39][CH2:36][CH2:37]1参加物
6
実験手順
The title compound was prepared from 2-isopropyl-6-methoxy-1H-indole-3-carbaldehyde (Compound 137), 3-(bromomethyl)pyridine.HBr, 3,4-difluorobenzylamine, and cyclobutyl bromide by, in order, General Procedure J, General Procedure K, General Procedure C, General Procedure L, and General Procedure N.
出典と根拠
- ORDレコード
- ord-55f9e6fabcba425ab1c1072f1aee8be9
- 出典データセット
- uspto-grants-2013_09
- 特許番号
- US08524917B2
関連ノート
読み込み中…