Methyl 4-(methylamino)-3-nitrobenzoate → Methyl 3-amino-4-(methylamino)benzoate

HRID 410826

反応式

HRID 410826 の反応式
[CH3:1][O:2][C:3](=[O:15])[C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH3:11])=[C:6]([N+:12]([O-])=O)[CH:5]=1>[Pd]>[CH3:1][O:2][C:3](=[O:15])[C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH3:11])=[C:6]([NH2:12])[CH:5]=1

参加物

3

反応物 1

HCID 7650848Methyl 4-(methylamino)-3-nitrobenzoate

生成物 1

HCID 15586064Methyl 3-amino-4-(methylamino)benzoate収率 96.1%

試薬・触媒・溶媒 1

HCID 23938Palladium触媒

実験手順

3-amino-4-methylamino-benzoic acid methyl ester (677 mg) was prepared by following General Procedure B starting from 4-methylamino-3-nitro-benzoic acid methyl ester (822 mg) and Pd/C (10% by weight, 82 mg). The crude product was used in the next step without further purification.

後処理

  1. customThe crude product was used in the next step without further purification

出典と根拠

ORDレコード
ord-4518beb51d0246db85a61f63cb1016c4
出典データセット
uspto-grants-2014_06
特許番号
US08759535B2

関連ノート

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