3-(2-Nitrophenyl)acrylic acid → Hydrocarbostyril

HRID 414551

反応式

HRID 414551 の反応式
[N+:1]([C:4]1[CH:14]=[CH:13][CH:12]=[CH:11][C:5]=1[CH:6]=[CH:7][C:8](O)=[O:9])([O-])=O>C(O)C.[Pd]>[NH:1]1[C:4]2[C:5](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH2:6][CH2:7][C:8]1=[O:9]

参加物

4

反応物 1

HCID 928203-(2-Nitrophenyl)acrylic acid

生成物 1

HCID 64796Hydrocarbostyril

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

A solution of 25 g of o-nitrocinnamic acid in 250 ml of ethanol was shaken with 2.5 g of 10% palladium on carbon under hydrogen at a pressure of 3 atmospheres. When the theoretical amount of hydrogen had been absorbed the catalyst was filtered off, washed with hot ethanol and the filtrate evaporated under reduced pressure to give 3,4-dihydrocarbosytril, m.p. 168°-169° C.

後処理

  1. customWhen the theoretical amount of hydrogen had been absorbed the catalyst
  2. filtrationwas filtered off
  3. washwashed with hot ethanol
  4. customthe filtrate evaporated under reduced pressure
  5. customto give 3,4-dihydrocarbosytril

出典と根拠

ORDレコード
ord-5ddb15b8e8ef4e80b242fcfb9689bd83
出典データセット
uspto-grants-1988_12
特許番号
US04792561

関連ノート

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