Nitric Acid → 4-Methyl-6-nitro-7-hydroxy-1-indanone

HRID 414675

反応式

HRID 414675 の反応式
[CH3:1][C:2]1[CH:10]=[CH:9][C:8]([OH:11])=[C:7]2[C:3]=1[CH2:4][CH2:5][C:6]2=[O:12].C(OC(=O)C)(=O)C.[N+:20]([O-])([OH:22])=[O:21]>C(O)(=O)C>[CH3:1][C:2]1[CH:10]=[C:9]([N+:20]([O-:22])=[O:21])[C:8]([OH:11])=[C:7]2[C:3]=1[CH2:4][CH2:5][C:6]2=[O:12]

参加物

5

反応物 3

HCID 944Nitric AcidHCID 7918Acetic AnhydrideHCID 124362447-Hydroxy-4-methyl-1-indanone

生成物 1

HCID 136041424-Methyl-6-nitro-7-hydroxy-1-indanone

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒2 回

実験手順

Into a solution of 25.6 g of 4-methyl-7-hydroxy-1-indanone in 250 ml of acetic acid was added 19.4 ml of acetic anhydride and a solution of 15.4 ml of concentrated nitric acid in 50 ml of acetic acid gradually. The reaction mixture was concentrated to drynsss, and the residue was washed with ether to obtain 25.7 g of 4-methyl-6-nitro-7-hydroxy-1-indanone.

後処理

  1. concentrationThe reaction mixture was concentrated
  2. washthe residue was washed with ether

出典と根拠

ORDレコード
ord-5cb9e452ae114983b72b93924d0f9940
出典データセット
uspto-grants-1988_12
特許番号
US04792628

関連ノート

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