2,2,2-Trifluoroethanol → 2-(2,2,2-Trifluoroethoxy)ethan-1-ol
反応式
[F:1][C:2]([F:6])([F:5])[CH2:3][OH:4].[O:7]1[CH2:11][CH2:10]OC1=O>CCN(CC)CC>[F:1][C:2]([F:6])([F:5])[CH2:3][O:4][CH2:10][CH2:11][OH:7]参加物
4
反応条件
- 温度
- 100 °C
実験手順
2,2,2-trifluoroethanol (15 g), 1,3-dioxolan-2-one (19.8 g) and Et3N (15 g) were mixed together, and then the mixture was heated to 100° C. and stirred for 24 h. Then the reaction mixture was distilled to obtain intermediate BR (12.7 g).
後処理
- distillationThen the reaction mixture was distilled
- customto obtain intermediate BR (12.7 g)
出典と根拠
- ORDレコード
- ord-30655cb2a7d84943813024b34a828b71
- 出典データセット
- uspto-grants-2012_01
- 特許番号
- US08106021B2
反応ノート
読み込み中…