Isonicotinic Acid → Isonicotinoyl chloride hydrochloride

HRID 42628

反応式

HRID 42628 の反応式
[C:1]([OH:9])(=O)[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1.S(Cl)([Cl:12])=O>>[ClH:12].[C:1]([Cl:12])(=[O:9])[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1

参加物

3

反応物 2

HCID 5922Isonicotinic AcidHCID 24386Thionyl Chloride

生成物 1

HCID 12262826Isonicotinoyl chloride hydrochloride

実験手順

A solution of isonicotinic acid (0.10 g, 0.8 mmol) and thionyl chloride (1 mL) were heated to reflux for 2 h and concentrated. The product obtained was used immediately in the following step.

後処理

  1. temperatureto reflux for 2 h
  2. concentrationconcentrated
  3. customThe product obtained

出典と根拠

ORDレコード
ord-0d0bda2a4ecf4b5fa1825fca2cb4ad7b
出典データセット
uspto-grants-2013_09
特許番号
US08536194B2

関連ノート

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