Acetonitrile → 3-(4-(Acryloyloxy)butoxy)-2-hydroxypropyl 2-benzoylbenzoate

HRID 42733

反応式

HRID 42733 の反応式
[C:1]([C:9]1[CH:17]=[CH:16][CH:15]=[CH:14][C:10]=1[C:11]([OH:13])=[O:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(#N)C.C([C:25]1C=C(C)C=[C:27](C(C)(C)C)[C:26]=1[OH:36])(C)(C)C.[OH:37][CH2:38][CH2:39][CH2:40][CH2:41][O:42][C:43](=[O:46])[CH:44]=[CH2:45].C(OCC1OC1)C1OC1>[Br-].C([N+](CCCC)(CCCC)CCCC)CCC.CC(N(C)C)=O>[C:43]([O:42][CH2:41][CH2:40][CH2:39][CH2:38][O:37][CH2:25][CH:26]([OH:36])[CH2:27][O:12][C:11](=[O:13])[C:10]1[CH:14]=[CH:15][CH:16]=[CH:17][C:9]=1[C:1](=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)(=[O:46])[CH:44]=[CH2:45]

参加物

7

反応物 4

HCID 6342AcetonitrileHCID 68132-Benzoylbenzoic AcidHCID 314042,6-Di-tert-butyl-4-methylphenolHCID 223231504-Hydroxybutylacrylate glycidylether

生成物 1

HCID 583255113-(4-(Acryloyloxy)butoxy)-2-hydroxypropyl 2-benzoylbenzoate

試薬・触媒・溶媒 2

HCID 74236Tetrabutylammonium Bromide触媒HCID 31374Dimethylacetamide溶媒

実験手順

A reaction mixture containing 2-benzoyl benzoic acid (40.0 g, 0.1722 mol), acetonitrile (300 mL), dimethylacetamide (10 mL), tetrabutylammonium bromide (5.6 g, 17.22 mmol) and 2,6-di-tert-butyl-4-methylphenol (0.3 g, 1.4 mmol) was heated to reflux. At this temperature 4-hydroxybutylacrylate glycidylether (28.0 g, 140 mmol) was added and the mixture was allowed to stir at reflux temperature for 16 hours.

後処理

  1. temperaturewas heated to reflux
  2. temperatureat reflux temperature for 16 hours

出典と根拠

ORDレコード
ord-320c13860a99488e881a36e355cfd6ef
出典データセット
uspto-grants-2013_09
特許番号
US08536217B2

関連ノート

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