1,1,3,3-Tetramethylbutyl isocyanide → [5-(2,4-Dimethyl-phenyl)-imidazo[1,2-b][1,2,4]triazol-6-yl]-(1,1,3,3-tetramethyl-butyl)-amine

HRID 431232

反応式

HRID 431232 の反応式
[NH2:1][C:2]1[N:6]=[CH:5][NH:4][N:3]=1.[CH3:7][C:8]([N+:15]#[C-:16])([CH3:14])[CH2:9][C:10]([CH3:13])([CH3:12])[CH3:11].[CH3:17][C:18]1[CH:25]=[C:24]([CH3:26])[CH:23]=[CH:22][C:19]=1[CH:20]=O>Cl(O)(=O)(=O)=O>[CH3:17][C:18]1[CH:25]=[C:24]([CH3:26])[CH:23]=[CH:22][C:19]=1[C:20]1[N:1]=[C:2]2[N:6]=[CH:5][NH:4][N:3]2[C:16]=1[NH:15][C:8]([CH3:14])([CH3:7])[CH2:9][C:10]([CH3:13])([CH3:12])[CH3:11]

参加物

5

反応物 3

HCID 267251,1,3,3-Tetramethylbutyl isocyanideHCID 618142,4-DimethylbenzaldehydeHCID 178418311HCID 178418311、化合物

生成物 1

HCID 22335554[5-(2,4-Dimethyl-phenyl)-imidazo[1,2-b][1,2,4]triazol-6-yl]-(1,1,3,3-tetramethyl-butyl)-amine

試薬・触媒・溶媒 1

HCID 24247Perchloric Acid溶媒

実験手順

Compound 53 was prepared in accordance with the general synthesis instructions from 1.0 ml (0.1 mmol) 3-amino-1,2,4-triazole solution (0.1 M, MC), 0.575 ml (0.115 mmol) 1,1,3,3-tetramethylbutylisonitrile solution (0.2 M, MC), 0.500 ml (0.15 mmol) 2,4-dimethylbenzaldehyde solution (0.3 M, MC) and 10 μl perchloric acid (w=20%).

出典と根拠

ORDレコード
ord-fd21a921329d43f78dd65c94765c26a7
出典データセット
uspto-grants-2003_12
特許番号
US06657064B2

関連ノート

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