Tetrahydrothiophene → Methyl-tetrahydrothiophene triflate

HRID 43294

反応式

HRID 43294 の反応式
[S:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:6][O:7][S:8]([C:11]([F:14])([F:13])[F:12])(=[O:10])=[O:9]>ClCCl>[OH:10][S:8]([C:11]([F:14])([F:13])[F:12])(=[O:9])=[O:7].[CH3:6][CH:2]1[CH2:3][CH2:4][CH2:5][S:1]1

参加物

4

反応物 2

HCID 1127TetrahydrothiopheneHCID 9526Methyl triflate

生成物 1

HCID 87659244Methyl-tetrahydrothiophene triflate

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

11 mmol of tetrahydrothiophene was dissolved in 10 ml of dichloromethane at 0° C., and about 12 mmol of methyltrifluoromethane sulfonate was slowly dripped to the mixture. As a result, a white solid product in a salt form was obtained after about 5 minutes. The solid product was filtered and dried for 1 hour in an oven at 50° C. to obtain the following product:

後処理

  1. customAs a result, a white solid product in a salt form was obtained after about 5 minutes
  2. filtrationThe solid product was filtered
  3. customdried for 1 hour in an oven at 50° C.
  4. customto obtain the following product

出典と根拠

ORDレコード
ord-9dffcd1064074e23ac42b75b8afab9eb
出典データセット
uspto-grants-2013_09
特許番号
US08536347B2

関連ノート

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