Kanamycin → Pantothenic Acid

HRID 433054

反応式

HRID 433054 の反応式
[C:1]([O-:15])(=[O:14])[CH2:2][CH2:3][NH:4][C:5](=[O:13])[C@@H:6]([C:8]([CH2:11][OH:12])([CH3:10])[CH3:9])[OH:7].C1[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](N)[C@H]2O)[C@@H]1N.N[C@H](C(O)=O)[C@H](CC)C.C[C@]1(O)[C@@H]2C(=C(O)[C@]3(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@@H]3C2)C(=O)C2C(O)=CC=CC1=2>>[C:1]([OH:15])(=[O:14])[CH2:2][CH2:3][NH:4][C:5](=[O:13])[C@@H:6]([C:8]([CH2:11][OH:12])([CH3:10])[CH3:9])[OH:7]

参加物

5

反応物 4

HCID 6032KanamycinHCID 6306L-IsoleucineHCID 167945(R)-PantothenateHCID 178418840HCID 178418840、化合物

生成物 1

HCID 6613Pantothenic Acid

実験手順

The formation of pantothenate by the C. glutamicum strains ATCC13032ΔilvA/pND-D2 and ATCC13032ΔilvA/pND-D2, pT-pfkAexp was tested in medium CGXII (Keilhauer et al., 1993, Journal of Bacteriology, 175:5595-5603; table 1), which had been supplemented with 25 μg/ml kanamycin, 2 mM isoleucine and in the case of the strain ATCC13032ΔilvA/pND-D2, pT-pfkAexp with additionally 10 μg/ml tetracycline.

出典と根拠

ORDレコード
ord-0a4c5d40d25443239827f11fa4bf233a
出典データセット
uspto-grants-2003_12
特許番号
US06667166B2

関連ノート

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