Water → 3-Formylchromone
反応式
[OH:1][CH2:2][C:3]1[C:12](=[O:13])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[O:5][CH:4]=1.O>[N+]([O-])(O)=O>[CH:2]([C:3]1[C:12](=[O:13])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[O:5][CH:4]=1)=[O:1]参加物
4
反応条件
- 温度
- 25 °C
実験手順
A quantity of 35.2 g. (0.2 mole) of 3-(hydroxymethyl)-chromone is dissolved in 250 ml of concentrated nitric acid with stirring at 25° C. There is no initial heat of reaction. The temperature gradually rises to 30° C over the next several minutes and is kept there for about 5 minutes with ice-acetone bath cooling. Water, 600 ml, is added to the reaction solution. The separated, pale yellow solid is filtered, washed well with water and dried to give 25 g. of crude aldehyde melting at 145°-148°.
後処理
- temperatureno initial heat of reaction
- customgradually rises to 30° C over the next several minutes
- temperaturecooling
- filtrationThe separated, pale yellow solid is filtered
- washwashed well with water
- customdried
- customto give 25 g
出典と根拠
- ORDレコード
- ord-854b5559993e4acc9f7bd78eb146b881
- 出典データセット
- uspto-grants-1977_02
- 特許番号
- US04008252
反応ノート
読み込み中…