Hydrochloric Acid → N-(4-carboxy-phenyl)-N-methyl-terephthalamic acid

HRID 440820ノート

反応式

HRID 440820 の反応式
C[O:2][C:3](=[O:24])[C:4]1[CH:23]=[CH:22][C:7]([C:8]([N:10]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([O:20]C)=[O:19])=[CH:14][CH:13]=2)[CH3:11])=[O:9])=[CH:6][CH:5]=1.[OH-].[Na+].Cl>C(#N)C>[C:18]([C:15]1[CH:14]=[CH:13][C:12]([N:10]([CH3:11])[C:8](=[O:9])[C:7]2[CH:22]=[CH:23][C:4]([C:3]([OH:24])=[O:2])=[CH:5][CH:6]=2)=[CH:17][CH:16]=1)([OH:20])=[O:19]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 54006989N-(4-methoxycarbonylphenyl)-N-methyl-terephthalamic acid methyl ester

生成物 1

HCID 22404898N-(4-carboxy-phenyl)-N-methyl-terephthalamic acid

試薬・触媒・溶媒 1

HCID 6342Acetonitrile溶媒

実験手順

0.99 g of N-(4-methoxycarbonylphenyl)-N-methyl-terephthalamic acid methyl ester was dissolved in 10 ml of acetonitrile and treated with 10 ml of 1N sodium hydroxide solution and the reaction mixture was stirred at room temperature for 16 hours. The mixture was then acidified with 1N hydrochloric acid and the resulting precipitate was filtered off yielding N-(4-carboxy-phenyl)-N-methyl-terephthalamic acid, which was used directly in the next step.

後処理

  1. filtrationthe resulting precipitate was filtered off

出典と根拠

ORDレコード
ord-148c016425eb4d998ae972f565a68b75
出典データセット
uspto-grants-1996_05
特許番号
US05521160

反応ノート

読み込み中…