Undecanoic Acid → Undecanoyl chloride

HRID 440971

反応式

HRID 440971 の反応式
[C:1]([OH:13])(=O)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].C(Cl)(=O)C([Cl:17])=O>C(Cl)Cl.CN(C)C=O>[C:1]([Cl:17])(=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11]

参加物

5

反応物 2

HCID 8180Undecanoic AcidHCID 65578Oxalyl chloride

生成物 1

HCID 87287Undecanoyl chloride収率 39.8%

試薬・触媒・溶媒 2

HCID 6228Dimethylformamide触媒HCID 6344Dichloromethane溶媒

実験手順

Under a nitrogen atmosphere, a solution of 5.0 grams (0.027 mole) of undecanoic acid in 75 mL of methylene chloride was stirred and 2.8 ml (0.032 mole) of oxalyl chloride and 5 drops of N,N-dimethylformamide were added. Upon completion of addition, the reaction mixture was stirred for about 16 hours, then it was concentrated under reduced pressure, yielding 2.2 grams of undecanoyl chloride.

後処理

  1. additionUpon completion of addition
  2. concentrationit was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-6e366cb4a7924555947d4f40ba8a8ff0
出典データセット
uspto-grants-1996_05
特許番号
US05521192

関連ノート

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