5-Chloro-2-nitrobenzoic acid → 5-Chloro-2-nitrobenzoyl chloride
反応式
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N+:11]([O-:13])=[O:12])=[C:6]([CH:10]=1)[C:7](O)=[O:8].S(Cl)([Cl:16])=O>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N+:11]([O-:13])=[O:12])=[C:6]([CH:10]=1)[C:7]([Cl:16])=[O:8]参加物
3
実験手順
100.00 g (0.50 mol) of 5-chloro-2-nitrobenzoic acid were mixed with 72.20 g (0.61 mol) of thionyl chloride and the mixture was heated under reflux for 2 h. The excess thionyl chloride was removed in vacuo. 106.50 g (ca. 98%) of crude 5-chloro-2-nitro-benzoyl chloride were obtained as an oil.
後処理
- temperaturethe mixture was heated
- temperatureunder reflux for 2 h
- customThe excess thionyl chloride was removed in vacuo
出典と根拠
- ORDレコード
- ord-98241a4d407344f4a0ba01242af87eef
- 出典データセット
- uspto-grants-2013_09
- 特許番号
- US08541410B2
反応ノート
読み込み中…