5-Chloro-2-nitrobenzoic acid → 5-Chloro-2-nitrobenzoyl chloride

HRID 44198

反応式

HRID 44198 の反応式
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N+:11]([O-:13])=[O:12])=[C:6]([CH:10]=1)[C:7](O)=[O:8].S(Cl)([Cl:16])=O>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N+:11]([O-:13])=[O:12])=[C:6]([CH:10]=1)[C:7]([Cl:16])=[O:8]

参加物

3

反応物 2

HCID 172865-Chloro-2-nitrobenzoic acidHCID 24386Thionyl Chloride

生成物 1

HCID 27236855-Chloro-2-nitrobenzoyl chloride収率 98%

実験手順

100.00 g (0.50 mol) of 5-chloro-2-nitrobenzoic acid were mixed with 72.20 g (0.61 mol) of thionyl chloride and the mixture was heated under reflux for 2 h. The excess thionyl chloride was removed in vacuo. 106.50 g (ca. 98%) of crude 5-chloro-2-nitro-benzoyl chloride were obtained as an oil.

後処理

  1. temperaturethe mixture was heated
  2. temperatureunder reflux for 2 h
  3. customThe excess thionyl chloride was removed in vacuo

出典と根拠

ORDレコード
ord-98241a4d407344f4a0ba01242af87eef
出典データセット
uspto-grants-2013_09
特許番号
US08541410B2

関連ノート

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