5-Methyl-2-nitrobenzoic acid → 5-Methyl-2-nitrobenzoyl chloride

HRID 44235

反応式

HRID 44235 の反応式
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([N+:11]([O-:13])=[O:12])=[C:6]([CH:10]=1)[C:7](O)=[O:8].S(Cl)([Cl:16])=O>>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([N+:11]([O-:13])=[O:12])=[C:6]([CH:10]=1)[C:7]([Cl:16])=[O:8]

参加物

3

反応物 2

HCID 183715-Methyl-2-nitrobenzoic acidHCID 24386Thionyl Chloride

生成物 1

HCID 30160135-Methyl-2-nitrobenzoyl chloride

実験手順

A mixture of 5-methyl-2-nitrobenzoic acid (3.6 g, 19.87 mmol) and thionyl chloride (18 mL) was stirred under reflux for 20 hours then concentrated under reduced pressure to give 5-methyl-2-nitrobenzoyl chloride (3.77 g) which was used without further purification.

後処理

  1. temperatureunder reflux for 20 hours
  2. concentrationthen concentrated under reduced pressure

出典と根拠

ORDレコード
ord-2380136c791e4cb694bce3db9ce279d8
出典データセット
uspto-grants-2013_09
特許番号
US08541407B2

関連ノート

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