Methanol → (R)-(+)-3,7-dimethyloctanoic acid
反応式
C([O:3][C:4](=[O:14])[CH2:5][C@H:6]([CH3:13])[CH2:7][CH2:8][CH2:9][CH:10]([CH3:12])[CH3:11])C.CO.C(Cl)(Cl)Cl>[OH-].[Na+]>[CH3:13][C@H:6]([CH2:7][CH2:8][CH2:9][CH:10]([CH3:12])[CH3:11])[CH2:5][C:4]([OH:14])=[O:3]参加物
5
実験手順
Hydrolysis: 400 mg. (2 mmol) of 3(R),7-dimethyl octanoic acid ethyl ester was refluxed in 6 N NaOH (1 ml.) and methanol (4 ml.) for 2 hours. It was worked up as in Example 10 to give 207 mg. (60% yield) of 3(R),7-dimethyl octanoic acid (R-(+)-dihydrocitronellic acid), [α]D25 + 6.81° (c=5.039, CHCl3).
後処理
- customHydrolysis
- customto give 207 mg
出典と根拠
- ORDレコード
- ord-e3a44969ee5e443b9f7ff047a3c13f26
- 出典データセット
- uspto-grants-1977_08
- 特許番号
- US04045475
反応ノート
読み込み中…