Acetic Acid → 4-Chloro-1-naphthol

HRID 443354

反応式

HRID 443354 の反応式
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([O:12]C)=[CH:4][CH:3]=1.C(O)(=O)C.Br>O>[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([OH:12])=[CH:4][CH:3]=1

参加物

5

反応物 3

HCID 176Acetic AcidHCID 260Hydrogen BromideHCID 6060381-Chloro-4-methoxynaphthalene

生成物 1

HCID 117874-Chloro-1-naphthol

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

The known compound 1-chloro-4-methoxynaphthalene is dissolved in 150 ml. of acetic acid and 150 ml. of 48 percent hydrobromic acid, and the mixture is heated at its reflux temperature for two hours. The mixture is diluted with 200 ml. of water and cooled to provide 1-chloro-4-hydroxynaphthalene as a crystalline solid.

後処理

  1. temperaturereflux temperature for two hours
  2. additionThe mixture is diluted with 200 ml

出典と根拠

ORDレコード
ord-70ee28ffc1904d83afb2e39dd9462ea4
出典データセット
uspto-grants-1981_04
特許番号
US04260547

関連ノート

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