Bromopyruvic Acid → 3-(Bromomethyl)-1,2-dihydroquinoxalin-2-one
反応式
[2H][C:2]1[C:7]([2H])=[C:6]([NH2:9])[C:5]([NH2:10])=[C:4]([2H])[C:3]=1[2H].[Br:13][CH2:14][C:15](=O)[C:16](O)=[O:17]>O1CCCC1>[Br:13][CH2:14][C:15]1[C:16](=[O:17])[NH:10][C:5]2[C:6]([N:9]=1)=[CH:7][CH:2]=[CH:3][CH:4]=2参加物
4
実験手順
O-phenylenediamine (1.0 g., 0.0092 mol.) was dissolved in tetrahydrofuran (50 ml.) and 3-bromopyruvic acid (1.7 g., 0.0102 mol.) added. The reaction mixture was stirred at room temperature for one hour, during which time the product precipitated as a yellow solid. The product was collected by filtration and crystallized from methylene chloride. (0.91 g., m.p. 221°-223° (dec.) 41%)
後処理
- customprecipitated as a yellow solid
- filtrationThe product was collected by filtration
- customcrystallized from methylene chloride
出典と根拠
- ORDレコード
- ord-a422bb2a765c42ceb676a1d2d0df4fbd
- 出典データセット
- uspto-grants-1981_04
- 特許番号
- US04262123
反応ノート
読み込み中…